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Does vitamin D3 and K2 help with weight loss in the UK?

Weight Management

Does vitamin D3 and K2 help with weight loss in the UK?

March 17, 2025

Yes, vitamins D3 and K2 may support weight management, but they aren't magic pills for weight loss. Here's what you need to know:

  • Vitamin D3: Helps regulate metabolism, improves glucose processing, and may reduce fat cell formation. Studies link higher vitamin D levels with lower BMI and waist circumference.
  • Vitamin K2: Directs calcium to bones and teeth, prevents arterial buildup, and may reduce visceral fat and body weight.

Key findings:

  • A 2018 study showed vitamin D3 supplementation reduced BMI and weight over 3 months.
  • A 2017 study linked higher K2 intake to less abdominal fat.

Why this matters in the UK:

  • Limited sunlight from October to March reduces natural vitamin D production, which may contribute to weight-related challenges.
  • Nearly half the global population has insufficient vitamin D levels, making supplementation essential, especially in regions with low sunlight exposure.

Dosage guidelines (UK):

  • Vitamin D3: 15–20 mcg (600–800 IU) daily.
  • Vitamin K2: ~100 mcg daily.

While these vitamins can support metabolism, appetite control, and fat distribution, they work best alongside a balanced diet and regular exercise. Always consult your healthcare provider before starting supplements.

Quick tip: Combine D3 and K2 supplements for better results, as they complement each other in calcium regulation and energy metabolism.

Curious about how to enhance fat burning? MCT oil may help boost metabolism and support weight management.

Research on D3 and K2 for weight loss

Discover how vitamins D3 and K2 may support weight management, with research-backed insights on their effects on metabolism, fat storage, and overall health.

Key study results

Recent studies suggest a connection between vitamin D3 and K2 and weight management. A meta-analysis of 11 randomized controlled trials found that supplementing with vitamin D3 (cholecalciferol) led to reductions in BMI by 0.32 kg/m² and waist circumference by 1.42 cm 

In a 2017 study spanning three years, higher vitamin K2 intake was linked to lower body weight and reduced visceral abdominal fat.

Here’s a closer look at two clinical trials that highlight these findings:

These results suggest a potential role for D3 and K2 in weight control.

Interestingly, research also shows that people with obesity often have lower vitamin D levels. Higher levels of vitamin D have been associated with better fat oxidation and increased energy use.

Research gaps and uncertainties

Despite the encouraging data, there are still some unanswered questions:

  • Many studies on vitamin D are observational rather than experimental, making it tough to confirm direct cause-and-effect relationships.
  • Trials often combine vitamin supplementation with diet or exercise changes, making it harder to isolate the effects of the vitamins themselves.

Key areas needing further exploration include:

  • Defining the optimal dosage and duration of vitamin D3 for weight management.
  • Examining its effects on specific body composition metrics, like fat mass percentage.
  • Clarifying its standalone role in weight loss.

Future research should focus on the long-term effects of combining vitamin D3 and K2, their impact on body composition markers, and ideal dosing strategies. This is especially important for regions like the UK, where sunlight exposure varies with the seasons.

How D3 and K2 affect body weight

Explore the role of vitamins D3 and K2 in fat storage, metabolism, and energy balance, and how they may influence body weight.

Effects on fat storage

Fat tissues store a significant portion (35%-75%) of total vitamin D. Vitamin D plays a role in fat cell behaviour, influencing their formation, how fat is stored, and how it's broken down for energy.

Studies also show that higher doses of calcitriol (1,25-dihydroxy vitamin D) can lower lipid buildup in fat cells. These processes also connect to how vitamin D affects hunger and energy balance.

Vively vs. Ozempic for weight loss—explore how these two approaches compare and which might be the better fit for your health goals.

Hunger and energy effects

Vitamin D₃ doesn’t just regulate fat storage; it also impacts appetite and energy use. When combined with calcium, it may help manage hunger and calorie burning. For example, a 15-week study of 63 overweight, middle-aged women found that calcium and vitamin D supplementation led to weight loss four times greater than the control group.

Interactions with other nutrients

Vitamin D₃ works alongside other nutrients to support metabolic health. Together, vitamins D₃ and K₂ enhance processes like thyroid function, insulin sensitivity, and calcium usage. Vitamin K₂, in particular, ensures calcium is used effectively, helps regulate hormones tied to fat metabolism, and improves insulin sensitivity. In muscle tissue, vitamin D₃ promotes protein synthesis, which further boosts calorie burning.

Safe usage and dosage guidelines

Learn the recommended daily intake, safe limits, and best practices for supplementing with vitamins D3 and K2 to support overall health.

UK dosage standards

In the UK, the government provides daily intake recommendations for vitamin D based on age groups. Adults aged 19–50 and 51–70 are advised to consume 15 micrograms (600 IU) of vitamin D3 daily, while those over 70 should aim for 20 micrograms (800 IU). For vitamin K2, a daily intake of around 100 micrograms is suggested. Additionally, the maximum safe limit for vitamin D3 is set at 4,000 IU per day.

Food sources and supplements

Boosting your intake of vitamin D3 and K2 can be done through natural food sources or supplements. Common vitamin D sources in the UK include fatty fish like salmon and mackerel, egg yolks, fortified cereals, and UV-exposed mushrooms. For vitamin K2, fermented foods and animal products are good options.

When selecting supplements, look for those that have undergone third-party testing. Regularly monitoring your nutrient levels can help you see the benefits of these dietary and supplement choices.

Health tracking tools

To get the most out of your supplementation, keeping an eye on your vitamin D levels and overall nutrient status is key. Vively’s lead dietitian, Charlotte Battle, highlights:

"Tracking your health helps you see how your body responds to supplementation, ensuring you get the right nutrients in the right amounts."

Here are some tips for monitoring and optimising supplementation:

  • Test your vitamin D levels before starting supplements.
  • Aim for blood levels between 30–60 ng/mL.
  • Take supplements with your first meal for better absorption.
  • Pair vitamin D with magnesium (200 mg twice daily) to improve absorption.
  • Track changes in weight and energy to evaluate effectiveness.

Be cautious of vitamin D toxicity, as blood levels above 100 ng/mL indicate overconsumption. Always consult your healthcare provider before starting any supplementation, especially if you are on medication or have pre-existing health conditions.

Ever wondered how blood sugar affects your weight? Stabilising your glucose levels can play a key role in managing cravings and supporting weight loss.

Summary and next steps

Research shows that maintaining healthy levels of vitamin D3 and K2 can support metabolic health, especially during times of limited sunlight. Studies suggest a connection between higher vitamin K2 levels and lower visceral fat. While these vitamins don't directly burn fat, they can contribute to better overall metabolism.

This is especially important for people in the UK, where sunlight exposure is minimal from October to March, limiting natural vitamin D production. Since individual requirements differ, consulting a healthcare provider for personalised advice is key to achieving the best results.

With these findings in mind, there are practical ways to include these vitamins in your weight management plan.

Getting started

Here are some steps to help you incorporate vitamin D3 and K2 into your routine:

  • Check your current levels: Start by consulting your healthcare provider to measure your vitamin D and K levels. This will help determine if supplements are needed and guide the right dosage.
  • Focus on natural sources: From late March to September, aim for about 10 minutes of daily sun exposure between 11 AM and 3 PM. Add these foods to your diet for a natural boost:
  • Adopt a well-rounded approach
    Pair supplementation with regular exercise and a balanced diet. Keep track of your progress and stay in touch with your healthcare provider to ensure your plan supports your weight management goals effectively.

Get irrefutable data about your diet and lifestyle by using your own glucose data with Vively’s CGM Program. We’re currently offering a 20% discount for our annual plan. Sign up here.

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Does vitamin D3 and K2 help with weight loss in the UK?
March 17, 2025

Does vitamin D3 and K2 help with weight loss in the UK?

Yes, vitamins D3 and K2 may support weight management, but they aren't magic pills for weight loss. Here's what you need to know:

  • Vitamin D3: Helps regulate metabolism, improves glucose processing, and may reduce fat cell formation. Studies link higher vitamin D levels with lower BMI and waist circumference.
  • Vitamin K2: Directs calcium to bones and teeth, prevents arterial buildup, and may reduce visceral fat and body weight.

Key findings:

  • A 2018 study showed vitamin D3 supplementation reduced BMI and weight over 3 months.
  • A 2017 study linked higher K2 intake to less abdominal fat.

Why this matters in the UK:

  • Limited sunlight from October to March reduces natural vitamin D production, which may contribute to weight-related challenges.
  • Nearly half the global population has insufficient vitamin D levels, making supplementation essential, especially in regions with low sunlight exposure.

Dosage guidelines (UK):

  • Vitamin D3: 15–20 mcg (600–800 IU) daily.
  • Vitamin K2: ~100 mcg daily.

While these vitamins can support metabolism, appetite control, and fat distribution, they work best alongside a balanced diet and regular exercise. Always consult your healthcare provider before starting supplements.

Quick tip: Combine D3 and K2 supplements for better results, as they complement each other in calcium regulation and energy metabolism.

Curious about how to enhance fat burning? MCT oil may help boost metabolism and support weight management.

Research on D3 and K2 for weight loss

Discover how vitamins D3 and K2 may support weight management, with research-backed insights on their effects on metabolism, fat storage, and overall health.

Key study results

Recent studies suggest a connection between vitamin D3 and K2 and weight management. A meta-analysis of 11 randomized controlled trials found that supplementing with vitamin D3 (cholecalciferol) led to reductions in BMI by 0.32 kg/m² and waist circumference by 1.42 cm 

In a 2017 study spanning three years, higher vitamin K2 intake was linked to lower body weight and reduced visceral abdominal fat.

Here’s a closer look at two clinical trials that highlight these findings:

These results suggest a potential role for D3 and K2 in weight control.

Interestingly, research also shows that people with obesity often have lower vitamin D levels. Higher levels of vitamin D have been associated with better fat oxidation and increased energy use.

Research gaps and uncertainties

Despite the encouraging data, there are still some unanswered questions:

  • Many studies on vitamin D are observational rather than experimental, making it tough to confirm direct cause-and-effect relationships.
  • Trials often combine vitamin supplementation with diet or exercise changes, making it harder to isolate the effects of the vitamins themselves.

Key areas needing further exploration include:

  • Defining the optimal dosage and duration of vitamin D3 for weight management.
  • Examining its effects on specific body composition metrics, like fat mass percentage.
  • Clarifying its standalone role in weight loss.

Future research should focus on the long-term effects of combining vitamin D3 and K2, their impact on body composition markers, and ideal dosing strategies. This is especially important for regions like the UK, where sunlight exposure varies with the seasons.

How D3 and K2 affect body weight

Explore the role of vitamins D3 and K2 in fat storage, metabolism, and energy balance, and how they may influence body weight.

Effects on fat storage

Fat tissues store a significant portion (35%-75%) of total vitamin D. Vitamin D plays a role in fat cell behaviour, influencing their formation, how fat is stored, and how it's broken down for energy.

Studies also show that higher doses of calcitriol (1,25-dihydroxy vitamin D) can lower lipid buildup in fat cells. These processes also connect to how vitamin D affects hunger and energy balance.

Vively vs. Ozempic for weight loss—explore how these two approaches compare and which might be the better fit for your health goals.

Hunger and energy effects

Vitamin D₃ doesn’t just regulate fat storage; it also impacts appetite and energy use. When combined with calcium, it may help manage hunger and calorie burning. For example, a 15-week study of 63 overweight, middle-aged women found that calcium and vitamin D supplementation led to weight loss four times greater than the control group.

Interactions with other nutrients

Vitamin D₃ works alongside other nutrients to support metabolic health. Together, vitamins D₃ and K₂ enhance processes like thyroid function, insulin sensitivity, and calcium usage. Vitamin K₂, in particular, ensures calcium is used effectively, helps regulate hormones tied to fat metabolism, and improves insulin sensitivity. In muscle tissue, vitamin D₃ promotes protein synthesis, which further boosts calorie burning.

Safe usage and dosage guidelines

Learn the recommended daily intake, safe limits, and best practices for supplementing with vitamins D3 and K2 to support overall health.

UK dosage standards

In the UK, the government provides daily intake recommendations for vitamin D based on age groups. Adults aged 19–50 and 51–70 are advised to consume 15 micrograms (600 IU) of vitamin D3 daily, while those over 70 should aim for 20 micrograms (800 IU). For vitamin K2, a daily intake of around 100 micrograms is suggested. Additionally, the maximum safe limit for vitamin D3 is set at 4,000 IU per day.

Food sources and supplements

Boosting your intake of vitamin D3 and K2 can be done through natural food sources or supplements. Common vitamin D sources in the UK include fatty fish like salmon and mackerel, egg yolks, fortified cereals, and UV-exposed mushrooms. For vitamin K2, fermented foods and animal products are good options.

When selecting supplements, look for those that have undergone third-party testing. Regularly monitoring your nutrient levels can help you see the benefits of these dietary and supplement choices.

Health tracking tools

To get the most out of your supplementation, keeping an eye on your vitamin D levels and overall nutrient status is key. Vively’s lead dietitian, Charlotte Battle, highlights:

"Tracking your health helps you see how your body responds to supplementation, ensuring you get the right nutrients in the right amounts."

Here are some tips for monitoring and optimising supplementation:

  • Test your vitamin D levels before starting supplements.
  • Aim for blood levels between 30–60 ng/mL.
  • Take supplements with your first meal for better absorption.
  • Pair vitamin D with magnesium (200 mg twice daily) to improve absorption.
  • Track changes in weight and energy to evaluate effectiveness.

Be cautious of vitamin D toxicity, as blood levels above 100 ng/mL indicate overconsumption. Always consult your healthcare provider before starting any supplementation, especially if you are on medication or have pre-existing health conditions.

Ever wondered how blood sugar affects your weight? Stabilising your glucose levels can play a key role in managing cravings and supporting weight loss.

Summary and next steps

Research shows that maintaining healthy levels of vitamin D3 and K2 can support metabolic health, especially during times of limited sunlight. Studies suggest a connection between higher vitamin K2 levels and lower visceral fat. While these vitamins don't directly burn fat, they can contribute to better overall metabolism.

This is especially important for people in the UK, where sunlight exposure is minimal from October to March, limiting natural vitamin D production. Since individual requirements differ, consulting a healthcare provider for personalised advice is key to achieving the best results.

With these findings in mind, there are practical ways to include these vitamins in your weight management plan.

Getting started

Here are some steps to help you incorporate vitamin D3 and K2 into your routine:

  • Check your current levels: Start by consulting your healthcare provider to measure your vitamin D and K levels. This will help determine if supplements are needed and guide the right dosage.
  • Focus on natural sources: From late March to September, aim for about 10 minutes of daily sun exposure between 11 AM and 3 PM. Add these foods to your diet for a natural boost:
  • Adopt a well-rounded approach
    Pair supplementation with regular exercise and a balanced diet. Keep track of your progress and stay in touch with your healthcare provider to ensure your plan supports your weight management goals effectively.

Get irrefutable data about your diet and lifestyle by using your own glucose data with Vively’s CGM Program. We’re currently offering a 20% discount for our annual plan. Sign up here.

Annia Soronio

Medical Writer

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